Biological Sciences

Bioinformatics Handles Big Data

Jason Moore, Third Century Professor and professor of genetics and community and family medicine at the Geisel School of Medicine, was driven to bioinformatics by a realization as a research intern that he enjoyed analyzing data more than gathering it.

In the 26th Presidential Faculty Lecture on March 31st, Jason Moore, Third Century Professor and professor of genetics and community and family medicine at the Geisel School of Medicine, gave a lecture on the growing field of bioinformatics and the future of big data. Starting with a brief history lesson,...


Nanoparticles: Designing Medicine at the Molecular Level

Six chemotherapy drugs commonly used to treat cancer.  Advances in nanoparticle technology will help reduce the awful side effects of these drugs.
Source: Wikimedia Commons

The greatest problem with traditional cancer treatments is lack of specificity. Treatments such as radiation therapy and chemotherapy kill healthy cells along with tumor cells, causing negative side effects in patients (1). Scientists believe that nanotechnology-based treatments can solve the issue of specificity. Nanoparticles used to treat cancer are approximately...


Narcolepsy as an Autoimmune Disease

Narcolepsy is a disorder that causes extreme daytime sleepiness and muscle weakness in patients. Source:

Mellin, Mignot, and colleagues recently found evidence supporting a view of narcolepsy as an autoimmune disease when they discovered CD4+ T cells that specifically target orexin’s precursor HCRT. Narcolepsy, a chronic disorder caused by a lack of orexin, has a strong genetic association with the antigen DQ0602; 98% of patients...


Transmissible Dog Cancer with Ancient Origins

Transmissible Dog Cancer with Ancient Origins

Throughout the 20th and 21st centuries, human cancer has been one of the largest enemies of the medical community. A malignant cancer cell’s range of possible mutations and oncogenesis complicates the processes of diagnosis and prevention. Recent research shows, however, that the world’s oldest known type of cancer, Canine Transmissible Venereal Tumor...


Antioxidants May Promote Cancer by Affecting Cancer-Preventing Genes

Vitamins and other supplements may not always help prevent cancer. Source:

Antioxidants are often hailed for their cancer-fighting effects for their ability to neutralize free radicals, reactive particles that can damage DNA. However, Swedish researchers have found that two such antioxidants, n-acetylcysteine (NAC) and vitamin E, can help cancer cells and tumors progress by affecting the work of p53, a protein...


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Founded in 1998, the Dartmouth Undergraduate Journal of Science aims to increase scientific awareness within the Dartmouth community by providing an interdisciplinary forum for sharing undergraduate research and enriching scientific knowledge.

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