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Narcolepsy as an Autoimmune Disease

Narcolepsy is a disorder that causes extreme daytime sleepiness and muscle weakness in patients. Source:

Mellin, Mignot, and colleagues recently found evidence supporting a view of narcolepsy as an autoimmune disease when they discovered CD4+ T cells that specifically target orexin’s precursor HCRT. Narcolepsy, a chronic disorder caused by a lack of orexin, has a strong genetic association with the antigen DQ0602; 98% of patients...


Transmissible Dog Cancer with Ancient Origins

Transmissible Dog Cancer with Ancient Origins

Throughout the 20th and 21st centuries, human cancer has been one of the largest enemies of the medical community. A malignant cancer cell’s range of possible mutations and oncogenesis complicates the processes of diagnosis and prevention. Recent research shows, however, that the world’s oldest known type of cancer, Canine Transmissible Venereal Tumor...


Cortisol as a Predictor of Clinical Depression

Molecular structure of cortisol. Source: Wiki Commons

  Major depressive disorder (MDD or MD) is a mental disorder that severely impairs the cognitive well-being of the victim and those around them. Its symptoms include a persistently low mood coupled with a self-reported lack of pleasure in everyday activities (1). Until now, practitioners have relied on subclinical depression...


Antioxidants May Promote Cancer by Affecting Cancer-Preventing Genes

Vitamins and other supplements may not always help prevent cancer. Source:

Antioxidants are often hailed for their cancer-fighting effects for their ability to neutralize free radicals, reactive particles that can damage DNA. However, Swedish researchers have found that two such antioxidants, n-acetylcysteine (NAC) and vitamin E, can help cancer cells and tumors progress by affecting the work of p53, a protein...


European Hunter-Gatherers had Dark Skin, Blue Eyes

European Hunter-Gatherers had Dark Skin, Blue Eyes

For much of its history, biological anthropology was largely been based on guesswork, drawing conclusions about ancient humans’ physiology from skeletal details alone. These skeletons tended to be incomplete, missing anywhere from a few long bones to everything but a few pieces of a skull. These incomplete findings caused debates...


Mission Statement

Founded in 1998, the Dartmouth Undergraduate Journal of Science aims to increase scientific awareness within the Dartmouth community by providing an interdisciplinary forum for sharing undergraduate research and enriching scientific knowledge.

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